I still have a Windows-based computer at home, and one of the major differences is the placement of the buttons used for shortcuts, such as copying and pasting. Sometimes I need to think for a split second before completing the action. It's not as annoying now, but this took a little while to get used to. Also, the structure of the Mac can be a little bit daunting until you understand their UI for the folder/directory structure. You can change the views for the display, but areas can be a little confusing when directories on different areas are named the same thing (such as 'Library'). I also prefer the Windows way to view photographs in directories, and the Mac way does take a little getting used to, but it is not as strong in my opinion. Despite these differences, I like the Mac.
As I am due to be changing jobs and realising that leaving the MacBook behind would put a hole in my life, I made a choice to purchase the MacBook Pro. I will be playing with this new toy and setting up my development environment onto it in the next few weeks.